"It warrants a discussion. It's totally legitimate for this to be raised," Biden said, adding that he'd spent "thousands of hours" at Senate hearings over the issue.
But Biden said that even if drug legalization might have benefits like reducing prison populations, it also would engender health problems, expand drug usage and even create bureaucracies for drug distribution.
"It impacts on a country's productivity. It impacts on the health costs of that country. It impacts on mortality rates. It's worth discussing," Biden told a group of journalists. "But there is no possibility that the Obama-Biden administration will change its policy on legalization."
There are some persuasive arguments on the other side.